Reproducibility, repeatability, and level of difficulty of two methods for tumor budding evaluation in oral squamous cell carcinoma.
Priscila Laiza Rubim LeãoHelvécio Marangon JuniorVictória Vasconcellos Moreira MeloÂngela Braga CaixetaPaulo Eduardo Alencar SouzaMaria Cássia Ferreira de AguiarMartinho Campolina Rebello HortaPublished in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2017)
In view of the unsatisfactory agreement between the two methods of tumor budding evaluation in OSCC, it is recommended that this evaluation should be performed by the immunostaining method for multicytokeratin, considering its higher reproducibility, greater replicability, and lower difficulty compared to the HE.
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