Reduced Hippocampal Volumes Partially Mediate Effects of Prenatal Alcohol Exposure on Spatial Navigation on a Virtual Water Maze Task in Children.

Neil C DodgeKevin G F ThomasErnesta M MeintjesChristopher D MoltenoJoseph L JacobsonSandra W Jacobson

Published in: Alcoholism, clinical and experimental research (2020)

These data confirm previous reports linking PAE to poorer spatial navigation on the VWM and are the first to provide direct evidence that volume reductions in this region partially mediate the relation of FASD diagnosis to place learning, suggesting that PAE specifically impairs the ability to encode the spatial information necessary for successful location of the hidden platform on a navigation task.

Keyphrases

pregnant women
young adults
high throughput
emergency department
electronic health record
big data
healthcare
health information
social media
data analysis