Comparison of treatment with insulin degludec and glargine U100 in patients with type 1 diabetes prone to nocturnal severe hypoglycaemia: The HypoDeg randomized, controlled, open-label, crossover trial.
Ulrik Pedersen-BjergaardRikke M AgesenJulie M B BrøsenAmra C AlibegovicHenrik U AndersenHenning Beck-NielsenPeter GustenhoffTroels K HansenChristoffer HedetoftTonny J JensenClaus B JuhlAndreas K JensenSusanne S LercheKirsten NørgaardHans-Henrik ParvingAnne L SørensenLise TarnowBirger ThorsteinssonPublished in: Diabetes, obesity & metabolism (2021)
Patients with T1D prone to nocturnal severe hypoglycaemia have lower rates of nocturnal symptomatic hypoglycaemia and all-day severe hypoglycaemia with insulin degludec compared with insulin glargine U100.
Keyphrases
- type diabetes
- open label
- glycemic control
- phase iii
- phase ii
- blood pressure
- obstructive sleep apnea
- clinical trial
- double blind
- early onset
- study protocol
- placebo controlled
- sleep apnea
- insulin resistance
- sleep quality
- drug induced
- phase ii study
- squamous cell carcinoma
- metabolic syndrome
- radiation therapy
- physical activity