Madin-Darby canine kidney cell sialic acid receptor modulation induced by culture medium conditions: Implications for the isolation of influenza A virus.
Sarah W NelsonJoshua N LorbachJacqueline M NoltingJason W StullDaral J JackwoodIan C DavisAndrew S BowmanPublished in: Influenza and other respiratory viruses (2019)
Medium conditions altered the distribution of SA receptors present on MDCK cells and affected IAV recovery. Culture in UltraMDCK SFM resulted in cells expressing both receptors and IAVs grew to higher titers than in the other culture condition, indicating that this medium may be useful for culturing IAV from multiple species.