A human microdose study of the antimalarial drug GSK3191607 in healthy volunteers.

Malek OkourGeo DerimanovRodger BarnettEsther FernandezSantiago FerrerStephanie GreshamMohammad HossainFrancisco-Javier GamoGavin KohAdrian PereiraKatie RolfeDeborah WongGraeme YoungHarshad RamiJohn Haselden

Published in: British journal of clinical pharmacology (2017)

The information generated by this study provides a basis for predicting the expected oral PK profiles of GSK3191607 in man and supports decisions on the future clinical development of the compound.

Keyphrases

signaling pathway
endothelial cells
healthcare
health information
plasmodium falciparum
drug induced