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Development of a novel magnetic particle-based agglutination immunoassay for anticardiolipin antibody detection in syphilis.

Mayur R ShuklaJohn W DeutschLara E PereiraEllen N KershYetunde F Fakile
Published in: Sexually transmitted infections (2020)
Preliminary evaluation of the novel NT-MAA validated proof of concept using laboratory-characterised syphilis sera and demonstrated performance comparable to RPR. Further validation of NT-MAA using additional specimens with better clinical staging may broaden the scope of developed test for syphilis diagnosis.
Keyphrases
  • men who have sex with men
  • human immunodeficiency virus
  • label free
  • lymph node
  • hepatitis c virus
  • antiretroviral therapy
  • hiv infected
  • real time pcr