Early treatment response to piperacillin/tazobactam in patients with bloodstream infections caused by non-ESBL ampicillin/sulbactam-resistant Escherichia coli: a binational cohort study.
Selma TobudicChristina ForstnerLisa SchneiderEmilia PaulussenLucie BartonickovaStefan HagelPeter StarzengruberHeinz BurgmannMathias W PletzPublished in: Infection (2023)
Our study suggests that initial use of PIP/TAZ may be associated with reduced early treatment response in E. coli BSI caused by AMP/SLB-resistant isolates compared to alternative monotherapies.