Spilanthol as a promising antifungal alkylamide for the treatment of vulvovaginal candidiasis.

Rodrigo Luiz FabriJhamine C O FreitasAri S O LemosLara M CamposIrley O M DinizNícolas C C PintoThiago P SilvaCinthia PalazziPaula MarchesiniCaio MonteiroAlan F BarbosaMário G CarvalhoLuciana M ChedierMarcelo Gonzaga de Freitas AraújoAna Carolina M ApolônioVinícius N RochaRossana C N MeloPriscila F Pinto

Published in: Medical mycology (2022)

This study sought to evaluate the antifungal activity of spilanthol against Candida albicans ATCC® 10 231™, a multidrug-resistant fungal strain. Our findings demonstrated that spilanthol(AcO) can be potentially considered for therapeutical treatment of vulvovaginal candidiasis caused by C. albicans.

Keyphrases

candida albicans
biofilm formation
multidrug resistant
escherichia coli
staphylococcus aureus
pseudomonas aeruginosa
smoking cessation