Optimal ICSI timing on immature oocytes for low prognosis patients under the POSEIDON classification.
Cheng ShiPing WangRong LiangMin FuSheng Nan DuanHuan ShenMei YangXi ChenPublished in: BMC pregnancy and childbirth (2024)
Our results revealed P-ICSI (ICSI was performed on in vitro matured oocytes 4-6 h after the first polar body extrusion) provided the most efficient method to utilize the immaturation oocytes basing on embryos utilization and live birth outcome for low prognosis patients under the POSEIDON classification. The mitochondria distribution of the in vitro matured oocytes' cytoplasm from P-ICSI varied that from R-ICSI.