Studies of the neurological symptoms and signs associated with the acute and late phases of infectious diseases are important in pandemic conditions. The novel coronavirus infection (COVID-19) pandemic has increased the number of patients with sleeplessness, this being an adverse prognostic factor for infections. This review addresses the factors and mechanisms of sleep impairments and their relationship with inflammation and immune system dysfunction in infectious diseases. In particular, impairments to the functioning of the melatoninergic system are discussed as the cause of sleeplessness during pandemics. The relevance of developing measures for rehabilitating patients, particularly use of Sonnovan to restore normal sleep, which plays a fundamental role in supporting people's mental and physical health, is emphasized.
Keyphrases
- infectious diseases
- prognostic factors
- sleep quality
- physical activity
- mental health
- oxidative stress
- end stage renal disease
- healthcare
- liver failure
- public health
- newly diagnosed
- ejection fraction
- chronic kidney disease
- coronavirus disease
- depressive symptoms
- peritoneal dialysis
- intensive care unit
- hepatitis b virus
- health information
- climate change
- acute respiratory distress syndrome
- patient reported