Clinical profiles and risk factors of 7-day and 30-day mortality among 160 pediatric patients with hemophagocytic lymphohistiocytosis.
Xun LiHaipeng YanXinping ZhangJiaotian HuangShi-Ting XiangZhenya YaoPing ZangDesheng ZhuZhenghui XiaoXiulan LuPublished in: Orphanet journal of rare diseases (2020)
The identified risk factors could help to stratify patients with high risk of early death, and need to be considered in the development of treatment protocols. As early mortality of HLH remains high, studies are needed to investigate how to initiate adequate HLH-directed treatment strategies for patients at higher risk of early death.