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Dermal Duct Tumor: A Diagnostic Dilemma.

Austinn C MillerSusuana AdjeiLaurie A TemizPavandeep GillAlfredo SillerStephen K Tyring
Published in: Dermatopathology (Basel, Switzerland) (2022)
Poromas or poroid tumors are a group of rare, benign cutaneous neoplasms derived from the terminal eccrine or apocrine sweat gland duct. There are four poroma variants with overlapping features: dermal duct tumor (DDT), eccrine poroma, hidroacanthoma simplex, and poroid hidradenoma, of which DDT is the least common. Clinically, the variants have a nonspecific appearance and present as solitary dome-shaped papules, plaques, or nodules. They can be indistinguishable from each other and a multitude of differential diagnoses, necessitating a better understanding of the characteristics that make the diagnosis of poroid neoplasms. However, there remains a paucity of information on these lesions, especially DDTs, given their infrequent occurrence. Herein, we review the literature on DDTs with an emphasis on epidemiology, pathogenesis, clinical features, diagnosis, and management.
Keyphrases
  • copy number
  • systematic review
  • risk assessment
  • risk factors
  • healthcare
  • wound healing
  • gene expression
  • dna methylation
  • rare case