Prognostic factors in patients with vulvar cancer: the VULCAN study.
Ignacio ZapardielSara IacoponiPluvio Jesús Coronado MartínKamil ZalewskiFrank ChenChristina FotopoulouPolat DursunIoannis C KotsopoulosRobert JachAlessandro BudaMaria J Martinez-SerranoChristoph GrimmRobert FruscioEnrique GarciaJacek Jan SznurkowskiCristina RuizMaria C NoyaDib BaraziJavier DiezBegoña Diaz De la NovalArnoldas BartuseviciusPierandrea De IacoMaria OteroMaria DiazDimitrios HaidopoulosSilvia FrancoPawel BlecharzMiguel A ZuñigaPatricia RubioBarbara GardellaDimitrios C PapatheodorouYusuf YildirimFrancesc FargasRonalds Macuksnull nullPublished in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2020)
Advanced patient age, number of positive inguinal lymph nodes, and lack of adjuvant treatment are significantly associated with a higher risk of relapse in patients with squamous cell vulvar cancer. Case volume per treating institution, FIGO stage, and stromal invasion appear to impact overall survival significantly. Future prospective trials are warranted to establish these prognostic factors for vulvar cancer.