Neurodevelopmental and behavioral outcomes of very preterm infants: latent profile analysis in the Environmental influences on Child Health Outcomes (ECHO) Program.
Marie CamerotaElisabeth C McGowanJudy AschnerAnnemarie StroustrupT Michael O'SheaJulie A HofheimerRobert M JosephRashelle MusciGenevieve TaylorBrian S CarterJennifer CheckLynne M DansereauSemsa GogcuJennifer B HeldermanCharles R NealSteven L PastyrnakLynne M SmithCarmen J MarsitBarry M Lesternull nullPublished in: Pediatric research (2023)
Most research on outcomes for children born very preterm have reported rates of impairment in single domains. Child-centered approaches describe profiles of children with unique combinations of cognitive, motor, and behavioral strengths and weaknesses. We capitalized on data from the nationwide Environmental influences on Child Health Outcomes Program to examine these profiles in a large sample of children born <33 weeks gestational age. We found four distinct neurobehavioral profiles consisting of different combinations of cognitive, motor, and behavioral characteristics. This information could aid in the development of clinical interventions that target different profiles of children with unique developmental needs.
Keyphrases
- gestational age
- preterm infants
- young adults
- low birth weight
- birth weight
- preterm birth
- mental health
- quality improvement
- magnetic resonance imaging
- magnetic resonance
- type diabetes
- physical activity
- metabolic syndrome
- skeletal muscle
- body mass index
- computed tomography
- insulin resistance
- electronic health record
- diffusion weighted imaging
- contrast enhanced
- artificial intelligence
- congenital heart disease