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The hAT-family transposable element, hopper, from Bactrocera dorsalis is a functional vector for insect germline transformation.

Alfred M HandlerMarc F Schetelig
Published in: BMC genetics (2020)
Both vectors were successfully used to transform D. melanogaster, and the DsRed vector was also used to transform the Caribbean fruit fly, Anastrepha suspensa, indicating a wide range of hopper function in dipteran species and, potentially, non-dipteran species. This vector provides a new tool for insect genetic modification for both functional genomic analysis and the control of insect populations.
Keyphrases
  • aedes aegypti
  • genetic diversity
  • genome wide
  • zika virus
  • copy number
  • dna methylation
  • gene therapy