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α-Amylase and dipeptidyl peptidase-4 (DPP-4) inhibitory effects of Melicope latifolia bark extracts and identification of bioactive constituents using in vitro and in silico approaches.

Alexandra QuekNur Kartinee KassimPei Cee LimDai Chuan TanMuhammad Alif Mohammad LatifAmin IsmailKhozirah ShaariKhalijah Awang
Published in: Pharmaceutical biology (2021)
The in vitro and in silico analyses indicated the potential of M. latifolia as an alternative source of α-amylase and DPP-4 inhibitors. Further pharmacological studies on the compounds are recommended.
Keyphrases
  • molecular docking
  • case control
  • human health
  • bioinformatics analysis
  • molecular dynamics simulations
  • essential oil