Pharmacokinetics of Antiretroviral Drugs in Older People Living with HIV: A Systematic Review.
Thainá Matos Palhaes ToledoThales CastroVanessa G OliveiraValdilea Gonçalves VelosoBeatriz Gilda Jegerhorn GrinsztejnSandra Wagner CardosoThiago Silva TorresRita EstrelaPublished in: Clinical pharmacokinetics (2023)
Exposure to DRV increases modestly with age, while exposure to BIC, DOR and RAL appears to be unaffected by age. As the available evidence to confirm a potential effect of aging on ARV pharmacokinetics is limited, further studies are necessary.