Antithrombotic Treatment for Stroke Prevention in Cervical Artery Dissection: The STOP-CAD Study.
Shadi YaghiLiqi ShuDaniel M MandelChristopher R Leon GuerreroNils HenningerJayachandra MuppaMuhammad AffanOmair Ul Haq LodhiMirjam Rachel HeldnerKateryna AntonenkoDavid SeiffgeMarcel ArnoldSetareh Salehi OmranRoss CrandallEvan LesterDiego Lopez MenaAntonio ArauzAhmad NehmeMarion BoulangerEmmanuel TouzeJoao Andre SousaJoao Sargento-FreitasVasco BarataPaulo Castro-ChavesMaria Teresa BritoMuhib KhanDania MallickAaron RothsteinOssama KhazaalJosefin E KaufmannStefan T EngelterChristopher TraenkaDiana Aguiar de SousaMafalda SoaresSara RosaLily W ZhouPreet GandhiThalia S FieldSteven ManciniIssa MetanisRonen R LekerKelly PanVishnu DantuKarl BaumgartnerTina BurtonRegina Von RennenbergChristian H NolteRichard ChoiJason MacDonaldReza Bavarsad ShahripourXiaofan GuoMalik GhannamMohammad AlmajaliEdgar A SamaniegoSebastian SanchezBastien RiouxFaycal Zine-EddineAlexandre PoppeAna Catarina FonsecaMaria Fortuna BaptistaDiana CruzMichele RomoliGiovanna De MarcoMarco LongoniZafer KeserKim GriffinLindsey KuohnJennifer FronteraJordan AmarJames GilesMarialuisa ZeddeRosario PascarellaIlaria GrisendiHipolito NzwaloDavid S LiebeskindAmir MolaieAnnie CavalierWayneho KamBrian Mac GrorySami Al KasabMohammad AnadaniKimberly KicielinskiAli EltatawyLina ChervakRoberto Chulluncuy-RivasYasmin AzizEkaterina BakradzeThanh Lam TranMarc Rodrigo-GisbertManuel RequenaFaddi Saleh VelezJorge Ortiz GraciaVarsha MudassaniAdam de HavenonVenugopalan Y VishnuSridhara YaddanapudiLatasha AdamsAbigail BrowngoehlTamra RanasingheRandy DunstonZachary LynchMary PenckoferJames SieglerSilvia MayerJoshua WilleyAdeel ZubairYee Kuang ChengRicha SharmaJoão Pedro MartoVítor Mendes FerreiraPiers KleinThanh N NguyenSyed Daniyal AsadZoha SarwatAnvesh BalabhadraShivam PatelThais SecchiSheila MartinsGabriel MantovaniYoung Dae KimBalaji KrishnaiahCheran ElangovanSivani LingamAbid QuereshiSebastian FridmanAlonso AlvaradoFarid KhasiyevGuillermo LinaresMarina ManninoValeria TerrusoSofia VassilopoulouVasilis TentolourisManuel Martinez-MarinoVictor Carrasco WallFransisca IndraswariSleiman El JamalShilin LiuMuhammad AlviFarman AliMohammed SarvathRami Z MorsiTareq Kass-HoutFeina ShiJinhua ZhangDilraj SokhiJamil SaidAlexis N SimpkinsRoberto GomezShayak SenMohammad GhaniMarwa ElnazeirHan XiaoNarendra KalaFarhan KhanChristoph StretzNahid MohammadzadehEric GoldsteinKaren FuriePublished in: Stroke (2024)
Our study does not rule out the benefit of anticoagulation in reducing ischemic stroke risk, particularly in patients with occlusive dissection. If anticoagulation is chosen, it seems reasonable to switch to antiplatelet therapy before 180 days to lower the risk of major bleeding. Large prospective studies are needed to validate our findings.