A diagnostic cohort study on the accuracy of 18-fluorodeoxyglucose (18FDG) positron emission tomography (PET)-CT for evaluation of malignancy in anterior mediastinal lesions: the DECiMaL study.
Chiara ProliPaulo De SousaSimon JordanVladimir AnikinAnand DevarajSusannah M LoveMichael ShackclothNikolaos KostoulasKostas PapagiannopoulosYama HaqzadMahmoud LoubaniFrancesco SellitriFelice GranatoAlexander BushAdrian MarchbankSwetha IyerMarco ScarciEric Limnull nullPublished in: BMJ open (2018)
The results of our study suggest reasonable sensitivity but no specificity implying that a negative PET/CT is useful to rule out the diagnosis of malignant disease whereas a positive result has no value in the discrimination between malignant and benign diseases of the anterior mediastinum.