An enrichment method to increase cell-free fetal DNA fraction and significantly reduce false negatives and test failures for non-invasive prenatal screening: a feasibility study.
Ping HuDong LiangYangyi ChenYing LinFengchang QiaoHang LiTing WangChunfang PengDonghong LuoHailiang LiuZhengfeng XuPublished in: Journal of translational medicine (2019)
We developed an effective method to enrich cffDNA for NIPS, which shows an increased success rate and a reduced chance of false negative comparing to the ordinary NIPS method.