Burden and Risk Factors of Contrast-Associated Acute Kidney Injury in Hospitalized Zambian Children: A Prospective Cohort Study at the University Teaching Hospitals.
Hellen M'hangoChishiba KabengeleVeronica SukuntuChisambo MwabaPublished in: Canadian journal of kidney health and disease (2023)
Using the ESUR criteria, a significant proportion (22.9%) of children undergoing contrast-enhanced computed tomography (CT) scans at the UTH developed CAAKI. In contrast, using the KDIGO criteria only 4.5% had CAAKI. Being born as a preterm baby, being female, having a higher eGFR at baseline, and receiving a higher dose of CM were found to be independent risk factors for CAAKI development in Zambian children. Most of the cases of CAAKI in children were transient and of little clinical significance as only a minority of patients developing CAAKI required kidney replacement therapy and all resolved by day 7 post administration of CM.
Keyphrases
- contrast enhanced
- computed tomography
- magnetic resonance imaging
- young adults
- magnetic resonance
- diffusion weighted
- risk factors
- replacement therapy
- end stage renal disease
- dual energy
- small cell lung cancer
- healthcare
- chronic kidney disease
- newly diagnosed
- diffusion weighted imaging
- smoking cessation
- low birth weight
- tyrosine kinase
- gestational age
- peritoneal dialysis
- preterm infants
- blood brain barrier
- subarachnoid hemorrhage
- medical students