Dissecting the role of TP53 alterations in del(11q) chronic lymphocytic leukemia.
Miguel Quijada-ÁlamoClaudia Pérez-CarreteroMaría Hernández-SánchezAna-Eugenia Rodríguez-VicenteAna-Belén HerreroJesús-María Hernández-SánchezMarta Martín-IzquierdoSandra Santos-MínguezMónica Del ReyTeresa GonzálezAraceli Rubio-MartínezAlfonso García de CocaJulio Dávila-VallsJosé-Ángel Hernández-RivasHelen ParkerJonathan C StreffordRocío BenitoJosé-Luis OrdóñezJesús María Hernández-RivasPublished in: Clinical and translational medicine (2021)
Our work highlights that combined monoallelic del(11q) and TP53 alterations coordinately contribute to clonal advantage and shorter overall survival in CLL.
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