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Unraveling Amentoflavone's Therapeutic Potential in Alzheimer's Disease: A Preclinical Assessment.

Sushma SinghNeetu AgrawalAhsas Goyal
Published in: Combinatorial chemistry & high throughput screening (2024)
Alzheimer's disease is one of the neurodegenerative diseases which causes cognition deficit. There are currently few medications available to treat Alzheimer's disease, even though researchers have devoted a great deal of time studying the condition and offering many benefits. Thus, only a few drugs are available for the treatment of Alzheimer's disease. Amentoflavone is a dietary component found in many plants and herbs that has several health advantages. Amentoflavone has demonstrated strong protective benefits against a range of brain illnesses in preclinical trials, most frequently in Alzheimer's disease. Amentoflavone, a biflavonoid, can be identified in a variety of herbs upon isolation. Considering the beneficial properties of this compound, this review emphasizes the pharmacological effects and botanical sources of amentoflavone, as well as the compound's benefits and possible applications in the treatment of Alzheimer's disorders.
Keyphrases
  • cognitive decline
  • healthcare
  • public health
  • mental health
  • mild cognitive impairment
  • white matter
  • multiple sclerosis
  • climate change
  • blood brain barrier
  • drinking water
  • resting state
  • smoking cessation