Natural Killer Lymphocytes Mediate Renal Fibrosis Due to Acute Cardiorenal Syndrome.

Kevin G Burfeind Yoshio Funahashi Adam C Munhall Mahaba B Eiwaz Michael P Hutchens

Published in: Kidney360 (2023)

Renal inflammation occurs during cardiorenal syndrome, which correlates with mesenchymal cell expansion. GzA, produced by NK cells, presents a novel therapeutic target to prevent the transition to CKD after AKI.

Keyphrases

nk cells
liver failure
stem cells
acute kidney injury
oxidative stress
case report
single cell
chronic kidney disease
bone marrow
cell therapy
peripheral blood
drug induced
hepatitis b virus
mesenchymal stem cells
mechanical ventilation