Chemical Review of Gorgostane-Type Steroids Isolated from Marine Organisms and Their 13 C-NMR Spectroscopic Data Characteristics.
Fahd M AbdelkaremMohamed E AbouelelaMohamed R KamelAlaa M NafadyAhmed E AllamIman A M Abdel-RahmanAhmad Abdulaziz A AlmatroudiFaris A AlrumaihiKhaled S AllemailemHamdy K AssafPublished in: Marine drugs (2022)
Gorgostane steroids are isolated from marine organisms and consist of 30 carbon atoms with a characteristic cyclopropane moiety. From the pioneering results to the end of 2021, isolation, biosynthesis, and structural elucidation using 13 C-NMR will be used. Overall, 75 compounds are categorized into five major groups: gorgost-5-ene, 5,6-epoxygorgostane, 5,6-dihydroxygorgostane, 9,11-secogorgostane, and 23-demethylgorgostane, in addition to miscellaneous gorgostane. The structural diversity, selectivity for marine organisms, and biological effects of gorgostane steroids have generated considerable interest in the field of drug discovery research.