The emergent invasive serotype 4 ST10172 strain acquires vanG type vancomycin-resistance element: A case of a 66-year-old with bacteremic pneumococcal pneumonia.
Sopio ChochuaBernard W BeallWuling LinTheresa TranJoy RiversZhongya LiMelissa L ArvayMiwako KobayashiJessica HoustonSabra AriasLesley McGeePublished in: The Journal of infectious diseases (2024)
We report a single case of invasive pneumococcal disease (IPD) by serotype 4, multilocus sequence type 10172 (serotype 4/ST10172) isolate with vanG-type resistance genes and reduced vancomycin susceptibility. The isolate was recovered during 2022 from a 66-year-old resident with bacteremic pneumococcal pneumonia within a CDC Active Bacterial Core surveillance (ABCs) site hospital. The patient had received 23-valent pneumococcal polysaccharide vaccine and there was no evidence of concurrent or prior receipt of vancomycin in the previous year. Serotype 4/ST10172 IPD has shown increases within western ABCs sites and the recent acquisition of a vanG element warrants close monitoring of this lineage.
Keyphrases
- dengue virus
- klebsiella pneumoniae
- methicillin resistant staphylococcus aureus
- zika virus
- public health
- healthcare
- escherichia coli
- urinary tract infection
- aedes aegypti
- case report
- patient safety
- squamous cell carcinoma
- radiation therapy
- locally advanced
- cell proliferation
- gene expression
- quality improvement
- transcription factor
- extracorporeal membrane oxygenation
- respiratory failure
- mechanical ventilation
- genome wide identification
- electronic health record