Identification of Novel T1D Risk Loci and Their Association With Age and Islet Function at Diagnosis in Autoantibody-Positive T1D Individuals: Based on a Two-Stage Genome-Wide Association Study.
Meng ZhuKuanfeng XuYang ChenYong GuMei ZhangFeihong LuoYu LiuWei GuJi HuHaixia XuZhiguo XieChengjun SunYuxiu LiMin SunXinyu XuHsiang-Ting HsuHeng ChenQi FuYun ShiJingjing XuLi JiJin LiuLingling BianJing ZhuShuang ChenLei XiaoXin LiHemin JiangMin ShenQianwen HuangChen FangXia LiGan HuangJingyi FanZhu JiangYue JiangJuncheng DaiHongxia MaShuai ZhengYun CaiHao DaiXuqin ZhengHongwen ZhouShining NiGuangfu JinJin-Xiong SheLiping YuConstantin PolychronakosZhibin HuZhiguang ZhouJian-Ping WengHongbing ShenYang TaoPublished in: Diabetes care (2019)
Our results extend current knowledge on genetic contributions to T1D risk. Further investigations in different populations are needed for genetic heterogeneity and subsequent precision medicine.