A novel isolation method for spontaneously released extracellular vesicles from brain tissue and its implications for stress-driven brain pathology.
Patrícia A GomesCristian BodoCarlos J Nogueras-OrtizMartina K SamiotakiMinghao ChenCarina Soares-CunhaJoana Margarida SilvaBárbara CoimbraGeorge M StamatakisLiliana SantosGeorge PanayotouFoteini TzouanouClarissa L WaitesChristos GatsogiannisNuno SousaDimitrios KapogiannisBruno Costa SilvaIoannis SotiropoulosPublished in: Cell communication and signaling : CCS (2023)
Overall, the spontaneous release method of sEV yield may contribute to the characterization and biomarker profile of physiologically relevant brain-derived sEVs in brain function and pathology. Video Abstract.