BIGwas: Single-command quality control and association testing for multi-cohort and biobank-scale GWAS/PheWAS data.
Jan Christian KässensLars WienbrandtDavid EllinghausPublished in: GigaScience (2022)
Researchers without extensive bioinformatics knowledge and with few computer resources can use BIGwas to perform multi-cohort GWAS with 1 million GWAS samples and, if desired, use it to build their own (genome-wide) PheWAS resource. BIGwas is freely available for download from http://github.com/ikmb/gwas-qc and http://github.com/ikmb/gwas-assoc.