Central Nervous System Effects of COVID-19 in People with HIV Infection.
Michael J PelusoJoanna HellmuthFelicia C ChowPublished in: Current HIV/AIDS reports (2021)
The convergence of the HIV and SARS-CoV-2 pandemics is an emerging field of interest. In this review, we outline the central nervous system (CNS) effects of COVID-19 in the general population and how these effects may manifest in people with HIV (PWH). We discuss the hypothetical mechanisms through which SARS-CoV-2 could impact the CNS during both the acute and recovery phases of infection and the potential selective vulnerability of PWH to these effects as a result of epidemiologic, clinical, and biologic factors. Finally, we define key research questions and considerations for the investigation of CNS sequelae of COVID-19 in PWH.
Keyphrases
- sars cov
- antiretroviral therapy
- respiratory syndrome coronavirus
- coronavirus disease
- hiv infected
- hiv positive
- blood brain barrier
- human immunodeficiency virus
- hiv testing
- hepatitis c virus
- hiv aids
- men who have sex with men
- rheumatoid arthritis
- cerebrospinal fluid
- liver failure
- intensive care unit
- risk assessment
- extracorporeal membrane oxygenation