Acute Regression in Down Syndrome.
Benjamin HandenIsabel C H ClareCharles LaymonMelissa PetersenShahid ZamanSid O'BryantDavneet MinhasDana TudorascuStephanie BrownBradley ChristianPublished in: Brain sciences (2021)
Some proteomics biomarker findings suggest that individuals with DS who experience acute regression may be at increased risk for AD at an earlier age in comparison to unaffected adults with DS. However, due to the age of the group (mean 38 years), it may be too early to observe meaningful group differences on image-based biomarkers.