GC/MSn analysis of the crude reaction mixtures from Friedel-Crafts acylation: Unambiguous identification and differentiation of 3-aroylbenzofurans from their 4- and 6-regioisomers.

Michela Bengala Michele Mancinelli Elias Quezada Giovanna Lucia Delogu

Published in: Rapid communications in mass spectrometry : RCM (2021)

The method allows the rapid characterization of crude reaction mixtures of benzoylbenzofurans using solely GC/MSn analysis, simplifying the workflow of extensive isolation and purification for structure elucidation.

Keyphrases

ionic liquid
gas chromatography
electronic health record
mass spectrometry
high resolution
loop mediated isothermal amplification