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White Matter Microstructural Differences in Youth With Classical Congenital Adrenal Hyperplasia.

Devyn L CotterAnisa AzadRyan P CabeenMimi S KimMitchell E GeffnerFarshid SepehrbandMegan M Herting
Published in: The Journal of clinical endocrinology and metabolism (2021)
These patterns of microstructure reflect less restricted water diffusion likely due to less coherency in oriented microstructure. These results suggest that white matter microstructural integrity in the fornix and stria terminalis is compromised and may be an additional related brain phenotype alongside affected hippocampus and amygdala neurocircuitry in individuals with CAH.
Keyphrases
  • white matter
  • multiple sclerosis
  • prefrontal cortex
  • functional connectivity
  • physical activity
  • mental health
  • resting state
  • young adults
  • cerebral ischemia
  • brain injury
  • subarachnoid hemorrhage
  • drug induced