A novel high performing multiplex immunoassay Multi-HTLV for serological confirmation and typing of HTLV infections.

Lola MarquéPeter LiehlJasper de Boer Hans PottelEdward L MurphyRoberta BruhnMars StoneZhanna KaidarovaTzong-Hae LeeMichael P Busch Maan Zrein

Published in: PLoS neglected tropical diseases (2021)

The newly developed Multi-HTLV is very competitive with currently used confirmatory assays and reduces considerably the number of indeterminate results. The multiparametric nature of the assay opens new avenues to study specific serological signatures of each patient, follow the evolution of infection, and explore utility for HTLV disease prognosis. Improving HTLV diagnostic testing will be critical to reduce transmission and to improve monitoring of seropositive patients.

Keyphrases

high throughput
end stage renal disease
newly diagnosed
case report
prognostic factors
gene expression
dna methylation
fine needle aspiration