Login / Signup

Effects of Sex, APOE4, and Lifestyle Activities on Cognitive Reserve in Older Adults.

Judy PaKaitlin B CasalettoKaitlin B CasalettoMiguel Arce RenteríaAmal HarratiSarah E TomNicole ArmstrongKumar RajanJustina Avila-RiegerYian GuNicole SchupfJennifer J ManlyAdam BrickmanLaura B Zahodne
Published in: Neurology (2022)
The associations of self-reported physical and cognitive activities with cognitive reserve are more pronounced in women, although APOE4 attenuates these associations. Future studies are needed to understand the causal relationship among sex, lifestyle activities, and genetic factors on cognitive reserve in older adults to best understand which lifestyle activities may be most beneficial and for whom.
Keyphrases
  • physical activity
  • metabolic syndrome
  • cardiovascular disease
  • weight loss
  • cognitive decline
  • type diabetes
  • gene expression
  • polycystic ovary syndrome
  • genome wide
  • copy number
  • current status
  • mild cognitive impairment