Urine Leucine-Rich α-2 Glycoprotein 1 (LRG1) Predicts the Risk of Progression to End-Stage Kidney Disease in Patients With Type 2 Diabetes.
Jian-Jun LiuSylvia LiuJiexun WangSharon L T PekJanus LeeResham L GurungKeven AngYi Ming ShaoSubramaniam TavintharanWern Ee TangChee Fang SumJian-Jun LiuPublished in: Diabetes care (2023)
Urine LRG1, a TGF-β signaling modulator, predicts risk of progression to ESKD independently of clinical risk factors in patients with type 2 diabetes, suggesting that it may be a novel factor involved in the pathophysiological pathway leading to kidney disease progression.