Endothelin-1 mediates Aspergillus fumigatus-induced airway inflammation and remodelling.
Briony LabramSara NamvarTracy HussellSarah E HerrickPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2019)
Our findings are consistent with the hypothesis that elevated endothelin-1 levels contribute to subepithelial thickening and highlight this factor as a possible therapeutic target for difficult-to-treat fungal-induced asthma.