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Eliminative Deoxofluorination Using XtalFluor-E: A One-Step Synthesis of Monofluoroalkenes from Cyclohexanone Derivatives.

Mathilde VandammeJean-François Paquin
Published in: Organic letters (2017)
The eliminative deoxofluorination of cyclohexanone derivatives using XtalFluor-E is described. The corresponding monofluoroalkenes are obtained in up to 79% yield. Notably, this one-step procedure occurs at room temperature using readily accessible and cost-effective reagents.
Keyphrases
  • room temperature
  • ionic liquid
  • structure activity relationship
  • minimally invasive