Wearable sensors detect impaired gait and coordination in LBSL during remote assessments.

Amena Smith FineMiriam KaufmanJordan GoodmanBela TurkAmy BastianDoris LinAli FatemiJennifer Keller

Published in: Annals of clinical and translational neurology (2022)

Wearable accelerometers are valid and sensitive for detecting ataxia in LBSL patients during remote assessments. The finding of large increases in the sway area during stance with the eyes closed is intriguing since dorsal column dysfunction is universally seen in LBSL. This approach can be applied to related rare diseases that feature ataxia.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
heart rate
early onset
spinal cord
machine learning
prognostic factors
deep learning
blood pressure
patient reported outcomes
low cost