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QTc prolongation in COVID-19 patients treated with hydroxychloroquine, chloroquine, azithromycin, or lopinavir/ritonavir: A systematic review and meta-analysis.

Carlos Diaz-ArocutipaAna Brañez-CondorenaAdrian V Hernandez
Published in: Pharmacoepidemiology and drug safety (2021)
COVID-19 patients treated with hydroxychloroquine/chloroquine with or without azithromycin had a relatively high prevalence and risk of QTc prolongation. However, the prevalence of arrhythmic events was very low, probably due to underreporting. The limited information about lopinavir/ritonavir showed that it does not prolong the QTc interval.
Keyphrases
  • coronavirus disease
  • sars cov
  • risk factors
  • antiretroviral therapy
  • respiratory syndrome coronavirus
  • plasmodium falciparum
  • health information