Mitochondria-targeted antioxidant SkQ1 suppresses fibrosarcoma and rhabdomyosarcoma tumour cell growth.

Ekaterina TitovaGalina S ShagievaOlga IvanovaLidiya DomninaMaria DomninskayaOlga StrelkovaNatalya KhromovaPavel B KopninBoris ChernyakVladimir SkulachevVera Dugina

Published in: Cell cycle (Georgetown, Tex.) (2018)

TPP+: Triphenylphosphonium cation; ROS: Reactive oxygen species; mtROS: Mitochondrial reactive oxygen species; NAC: N-acetyl-L-cysteine; DCFH-DA: Dichlorodihydrofluorescein diacetate; APC: Anaphase promoting complex; ABPs: Actin-binding proteins; DMEM: Dulbecco's modified Eagle media; SDS: sodium dodecyl sulfate; HEPES: 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid.

Keyphrases

reactive oxygen species
oxidative stress
transcription factor
signaling pathway
ionic liquid
cancer therapy
anti inflammatory
fluorescent probe
living cells
dna damage