Weekly Paclitaxel Administered During a Twin Pregnancy for Recurrent Breast Cancer: Case Report and Review of the Literature.
Serena GirardelliEmanuela RabaiottiFabio MauroOreste GentiliniPatrizia ZucchinelliRaffaella CioffiLuca ValsecchiGiorgia MangiliFedro A PeccatoriMassimo CandianiPublished in: Journal of adolescent and young adult oncology (2022)
Although cancer treatment during single pregnancy has been standardized, how to manage cancer diagnosed during a multiple gestation is still unclear. Chemotherapy during pregnancy has shown to be safe, however, there are reports of increased risks of fetal complications such as intrauterine growth restriction and preterm birth. Also, how to best adjust this to the pharmacokinetic characteristics of a twin gestation has yet to be fully investigated. We report the case of an IVF twin pregnancy with a diagnosis of breast cancer recurrence shortly after conception, and how the pregnancy was managed to obtain optimal obstetric, maternal/oncological, and fetal outcomes.
Keyphrases
- preterm birth
- gestational age
- pregnancy outcomes
- birth weight
- low birth weight
- pregnant women
- preterm infants
- type diabetes
- metabolic syndrome
- prostate cancer
- papillary thyroid
- radiation therapy
- locally advanced
- physical activity
- risk factors
- robot assisted
- squamous cell
- skeletal muscle
- atomic force microscopy
- glycemic control
- drug induced
- single molecule
- breast cancer risk