Selecting the dosage of ceftazidime-avibactam in the perfect storm of nosocomial pneumonia.
Shampa DasDiansong ZhouWright W NicholsAndy TownsendPaul NewellJianguo LiPublished in: European journal of clinical pharmacology (2019)
This work serves as a successful practical example of dosage design for a new antibacterial drug therapy in the indication of NP, including VAP, where previous drug therapies have failed, possibly as a result of evaluation of too few variables, thereby limiting the accuracy of pharmacodynamic predictions.