Mechanosensing by Gli1+ cells contributes to the orthodontic force-induced bone remodelling.
An-Qi LiuLi-Shu ZhangJi ChenBing-Dong SuiJin LiuQi-Ming ZhaiYan-Jiao LiMeng BaiKai ChenYan JinCheng-Hu HuFang JinPublished in: Cell proliferation (2020)
Our findings highlighted that Gli1+ cells in PDL directly respond to orthodontic force and further mediate bone remodelling, thus providing novel functional evidence in the mechanism of bone remodelling and first uncovering the mechanical responsive property of Gli1+ cells.