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Comparative analyses of two primate species diverged by more than 60 million years show different rates but similar distribution of genome-wide UV repair events.

Umit AkkoseVeysel Ogulcan KayaLaura Lindsey-BoltzZeynep KaragozAdam D BrownPeter A LarsenAnne D YoderAziz SancarOgün Adebali
Published in: BMC genomics (2021)
Our results suggest that mouse lemurs and humans, and possibly primates in general, share a homologous repair mechanism as well as genomic variance distribution, albeit with their variable repair efficiency. This result also emphasizes the deep homologies of individual tissue types across the eukaryotic phylogeny.
Keyphrases
  • genome wide
  • dna methylation
  • copy number
  • gene expression
  • dna repair
  • aqueous solution