Prophylactic fresh frozen plasma and platelet transfusion have a prothrombotic effect in patients with liver disease.
Fien A von MeijenfeldtBente P van den BoomJelle AdelmeijerLara N RobertsJ P LuyendykWilliam BernalPublished in: Journal of thrombosis and haemostasis : JTH (2020)
FFP and platelet transfusion resulted in increased thrombin generation and platelet counts in patients with liver disease, indicating a prothrombotic effect. However, whether all transfusions were truly indicated and had a clinically relevant effect is questionable.
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