Altered mRNA Expression of NFKB1 and NFKB2 Genes in Penile Lichen Sclerosus, Penile Cancer and Zoon Balanitis.
Piotr Mieczyslaw WierzbickiMateusz CzajkowskiAnna Kotulak-ChrząszczJustyna BukowiczKlaudia DzieciuchMałgorzata Sokołowska-WojdyłoZbigniew KmiećMatuszewski MarcinPublished in: Journal of clinical medicine (2022)
This is the first study regarding gene profiles of NFKB1/2 in PC and penile dermatoses. New drugs targeting modulation of canonical-activated NF-κB pathway should be studied and introduced to the treatment of PLS and PC apart from other treatments.
Keyphrases
- genome wide
- genome wide identification
- papillary thyroid
- radical prostatectomy
- signaling pathway
- prostate cancer
- squamous cell
- oxidative stress
- lps induced
- copy number
- squamous cell carcinoma
- cancer therapy
- dna methylation
- nuclear factor
- genome wide analysis
- childhood cancer
- lymph node metastasis
- replacement therapy
- solid state