Neoadjuvant chemotherapy enhances tumor-specific T cell immunity in patients with HPV-associated oropharyngeal cancer.
Christian SamaniegoJay FriedmanXinping YangChristopher BadgerTimothy ShaverShabnam SamankanPunam ThakkarJoseph F GoodmanArjun JoshiClint T AllenPublished in: Head & neck (2023)
NAC induces HPV-specific tumor T cell responses in patients with newly diagnosed HPV-associated OPSCC; whereas lack of an increase following NAC may associate with risk of relapse.