Impact of broad-spectrum antibiotic exposures and multidrug-resistant gram-negative bacteremia on hematopoietic cell transplantation outcomes.
Shaweta KaundalAditya JandialHarmandeep SinghMadhu ChopraKripa Shanker KasudhanNiranjan KhaireAlka KhadwalGaurav PrakashArihant JainVikas SuriAmol PatilAmit AroraVishal SharmaPallab RayPankaj MalhotraDeepesh P LadPublished in: Transplant infectious disease : an official journal of the Transplantation Society (2021)
This study shows pre- and post-HCT MDR GNB bacteremia is associated with an increased risk of severe acute GVHD and mortality. Patients with MDR GNB bacteremia had higher exposure to pre- and post-HCT carbapenems and colistin.