Evaluation of sirtuin 1 (SIRT1) levels in autosomal dominant polycystic kidney disease.
Pervin Ozkan KurtgozSuleyman KarakoseCigdem Damla CetinkayaEdip ErkusIbrahim GuneyPublished in: International urology and nephrology (2021)
Urine SIRT1 levels were lower in ADPKD patients than control group. The low urinary SIRT1 levels despite the similar blood SIRT1 levels might be due to the impaired metabolism of SIRT1 in ADPKD patients; this state might has a role in cyst development.